iccen.

Headword: 
iccen.
Principal English Translation: 

finally; once and for all; for the last time; to the end; forever

IPAspelling: 
iksen
Alonso de Molina: 

iccen. vltimadamente. (aduerbio.)
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 32r. col. 1. Thanks to Joe Campbell for providing the transcription.

Frances Karttunen: 

ICCEN once and for all / ultimadamente (M) The CEN element of this is undoubtedly CEM ‘one,’ but the IC element never occurs with a marked long vowel, so this is apparently not a simple compound of ĪC and CEM.
Frances Karttunen, An Analytical Dictionary of Nahuatl (Norman: University of Oklahoma Press, 1992), 92.