ezquiza.

Headword: 
ezquiza.
Principal English Translation: 

for a woman to menstruate (see Molina)

IPAspelling: 
eskiːsɑ
Alonso de Molina: 

ezquiza. n. (pret. onezquiz.) tener su costumbre la muger.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 29v. col. 2. Thanks to Joe Campbell for providing the transcription.

Frances Karttunen: 

EZQUĪZ(A) to bleed, to menstruate / tener su costumbre la mujer (M), sale sangre, sangra, se desangra (T) See EZ-TLI, QUĪZ(A). EZQUĪXTIĀ caus. EZQUĪZ(A)
Frances Karttunen, An Analytical Dictionary of Nahuatl (Norman: University of Oklahoma Press, 1992), 79.

Attestations from sources in English: 

Literally, for blood to emerge/flow.

themes: 
Sexuality, Fertility